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3.11: Medical Imaging - Biology

3.11: Medical Imaging - Biology


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Learning Objectives

  • Discuss the uses and drawbacks of X-ray imaging
  • Identify four modern medical imaging techniques and how they are used

For thousands of years, fear of the dead and legal sanctions limited the ability of anatomists and physicians to study the internal structures of the human body. An inability to control bleeding, infection, and pain made surgeries infrequent, and those that were performed—such as wound suturing, amputations, tooth and tumor removals, skull drilling, and cesarean births—did not greatly advance knowledge about internal anatomy. Theories about the function of the body and about disease were therefore largely based on external observations and imagination. During the fourteenth and fifteenth centuries, however, the detailed anatomical drawings of Italian artist and anatomist Leonardo da Vinci and Flemish anatomist Andreas Vesalius were published, and interest in human anatomy began to increase. Medical schools began to teach anatomy using human dissection; although some resorted to grave robbing to obtain corpses. Laws were eventually passed that enabled students to dissect the corpses of criminals and those who donated their bodies for research. Still, it was not until the late nineteenth century that medical researchers discovered non-surgical methods to look inside the living body.

X-Rays

German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible “ray” would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an “X-ray” image (as it came to be called) of his wife’s hand. Scientists around the world quickly began their own experiments with X-rays, and by 1900, X-rays were widely used to detect a variety of injuries and diseases. In 1901, Röntgen was awarded the first Nobel Prize for physics for his work in this field.

The X-ray is a form of high energy electromagnetic radiation with a short wavelength capable of penetrating solids and ionizing gases. As they are used in medicine, X-rays are emitted from an X-ray machine and directed toward a specially treated metallic plate placed behind the patient’s body. The beam of radiation results in darkening of the X-ray plate. X-rays are slightly impeded by soft tissues, which show up as gray on the X-ray plate, whereas hard tissues, such as bone, largely block the rays, producing a light-toned “shadow.” Thus, X-rays are best used to visualize hard body structures such as teeth and bones (Figure 1). Like many forms of high energy radiation, however, X-rays are capable of damaging cells and initiating changes that can lead to cancer. This danger of excessive exposure to X-rays was not fully appreciated for many years after their widespread use.

Refinements and enhancements of X-ray techniques have continued throughout the twentieth and twenty-first centuries. Although often supplanted by more sophisticated imaging techniques, the X-ray remains a “workhorse” in medical imaging, especially for viewing fractures and for dentistry. The disadvantage of irradiation to the patient and the operator is now attenuated by proper shielding and by limiting exposure.

Modern Medical Imaging

X-rays can depict a two-dimensional image of a body region, and only from a single angle. In contrast, more recent medical imaging technologies produce data that is integrated and analyzed by computers to produce three-dimensional images or images that reveal aspects of body functioning.

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a noninvasive imaging technique that uses computers to analyze several cross-sectional X-rays in order to reveal minute details about structures in the body (Figure 2). The technique was invented in the 1970s and is based on the principle that, as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates 360 degrees around the patient, taking X-ray images. A computer combines these images into a two-dimensional view of the scanned area, or “slice.”

Since 1970, the development of more powerful computers and more sophisticated software has made CT scanning routine for many types of diagnostic evaluations. It is especially useful for soft tissue scanning, such as of the brain and the thoracic and abdominal viscera. Its level of detail is so precise that it can allow physicians to measure the size of a mass down to a millimeter. The main disadvantage of CT scanning is that it exposes patients to a dose of radiation many times higher than that of X-rays. In fact, children who undergo CT scans are at increased risk of developing cancer, as are adults who have multiple CT scans.

A CT or CAT scan relies on a circling scanner that revolves around the patient’s body. Watch this video to learn more about CT and CAT scans. What type of radiation does a CT scanner use?

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Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device, which was in use clinically by the early 1980s. The early MRI scanners were crude, but advances in digital computing and electronics led to their advancement over any other technique for precise imaging, especially to discover tumors. MRI also has the major advantage of not exposing patients to radiation.

Drawbacks of MRI scans include their much higher cost, and patient discomfort with the procedure. The MRI scanner subjects the patient to such powerful electromagnets that the scan room must be shielded. The patient must be enclosed in a metal tube-like device for the duration of the scan (see Figure 2b), sometimes as long as thirty minutes, which can be uncomfortable and impractical for ill patients. The device is also so noisy that, even with earplugs, patients can become anxious or even fearful. These problems have been overcome somewhat with the development of “open” MRI scanning, which does not require the patient to be entirely enclosed in the metal tube. Patients with iron-containing metallic implants (internal sutures, some prosthetic devices, and so on) cannot undergo MRI scanning because it can dislodge these implants.

Functional MRIs (fMRIs), which detect the concentration of blood flow in certain parts of the body, are increasingly being used to study the activity in parts of the brain during various body activities. This has helped scientists learn more about the locations of different brain functions and more about brain abnormalities and diseases.

A patient undergoing an MRI is surrounded by a tube-shaped scanner. Watch this video to learn more about MRIs. What is the function of magnets in an MRI?

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Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving the use of so-called radiopharmaceuticals, substances that emit radiation that is short-lived and therefore relatively safe to administer to the body. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential. The main advantage is that PET (see Figure 2c) can illustrate physiologic activity—including nutrient metabolism and blood flow—of the organ or organs being targeted, whereas CT and MRI scans can only show static images. PET is widely used to diagnose a multitude of conditions, such as heart disease, the spread of cancer, certain forms of infection, brain abnormalities, bone disease, and thyroid disease.

PET relies on radioactive substances administered several minutes before the scan. Watch this video to learn more about PET. How is PET used in chemotherapy?

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Ultrasonography

Ultrasonography is an imaging technique that uses the transmission of high-frequency sound waves into the body to generate an echo signal that is converted by a computer into a real-time image of anatomy and physiology (see Figure 2d). Ultrasonography is the least invasive of all imaging techniques, and it is therefore used more freely in sensitive situations such as pregnancy. The technology was first developed in the 1940s and 1950s.

Ultrasonography is used to study heart function, blood flow in the neck or extremities, certain conditions such as gallbladder disease, and fetal growth and development. The main disadvantages of ultrasonography are that the image quality is heavily operator-dependent and that it is unable to penetrate bone and gas.


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Risk factors

Certain factors have been associated with an increased risk of developing fibroids. Women of African descent have the highest risk of fibroids compared with women of all other racial or ethnic backgrounds. 8 Age is also an important factor. Women who are age 40 to 50 years are more likely to have fibroids than younger women. 9 Other factors such as an early menarche (< age 10 years), a family history of fibroids, obesity, and nulliparity have also been associated with the development of fibroids. 9 Women who smoke, are multiparous, had a later menarche (> age 16 years), and have used oral contraceptives are less likely to develop fibroids. 2


Statistics for the Behavioral Sciences

Praised for its real-life applications, the text tells students when to use a particular statistic, why they should use it, and how the statistic should be computed and interpreted.

Author: James Jaccard

Publisher: Wadsworth Publishing Company

Now your students can become intelligent consumers of scientific research, without being overwhelmed by the statistics! Jaccard and Becker's text teaches students the basic skills for analyzing data and helps them become intelligent consumers of scientific information. Praised for its real-life applications, the text tells students when to use a particular statistic, why they should use it, and how the statistic should be computed and interpreted. Because many students, given a set of data, cannot determine where to begin in answering relevant research questions, the authors explicate the issues involved in selecting a statistical test. Each statistical technique is introduced by giving instances where the test is most typically applied followed by an interesting research example (each example is taken from psychology literature).


Diagnostics Industry Research & Market Reports

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Global Therapeutic Drug Monitoring Market Growth (Status and Outlook) 2021-2026

. of global Therapeutic Drug Monitoring market size (most likely outcome) will be a year-over-year revenue growth rate of XX% in 2021, from US$ 1581.7 million in 2020. Over the next five years the Therapeutic Drug . Read More

Global X-ray Imaging Market Growth 2021-2026

. size (most likely outcome) will be a year-over-year revenue growth rate of XX% in 2021, from US$ 12980 million in 2020. Over the next five years the X-ray Imaging market will register a 4.9% CAGR . Read More

Global Veterinary X-ray System Market Growth 2021-2026

. X-ray System market size (most likely outcome) will be a year-over-year revenue growth rate of XX% in 2021, from US$ 304.5 million in 2020. Over the next five years the Veterinary X-ray System market will . Read More

Global Dental X-ray Tube Market Growth 2021-2026

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Global Veterinary X-ray Market Growth (Status and Outlook) 2021-2026

. Veterinary X-ray market size (most likely outcome) will be a year-over-year revenue growth rate of XX% in 2021, from US$ 586.1 million in 2020. Over the next five years the Veterinary X-ray market will register . Read More

Global X-ray Ionizer Market Growth 2021-2026

. size (most likely outcome) will be a year-over-year revenue growth rate of XX% in 2021, from US$ 37 million in 2020. Over the next five years the X-ray Ionizer market will register a 17.6% CAGR . Read More

Diagnostic Reagent Markets in China

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Global SPECT and SPECT-CT Market Growth 2021-2026

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Diagnostic Reagent Industry Forecasts - China Focus

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Diagnostic Reagent Companies in China

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Global Portable Ultrasound Devices Market Growth 2021-2026

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Cancer Diagnostics Companies in China

. of the manufacturing capabilities and rising consumer consumptions in China have transformed China’s society and economy. China is one of the world’s major producers for industrial and consumer products. Far outpacing other economies in the . Read More

Cancer Diagnostics Markets in China

. economy maintains a high speed growth which has been stimulated by the consecutive increases of industrial output, imports & exports, consumer consumption and capital investment for over two decades. This new study examines China's economic . Read More

Cancer Diagnostics Industry Forecasts - China Focus

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Global Endoscopy Ultrasound Market Growth 2021-2026

. size (most likely outcome) will be a year-over-year revenue growth rate of XX% in 2021, from US$ 608.4 million in 2020. Over the next five years the Endoscopy Ultrasound market will register a 5.0% CAGR . Read More

Global Transplant Diagnostics Market Research Report 2021-2025

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Global Clinical Trial Imaging Market Growth (Status and Outlook) 2021-2026

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Global High Resolution 3D x-ray Microscope Market Growth 2021-2026

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Global Intraoral Dental X-ray Systems Market Growth 2021-2026

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Global Medical Battery Market Growth 2021-2026

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2021 North America Immunodiagnostics Market Perspective - USA, Canada, Mexico - Competitive Shares and SWOT Analysis, Volume and Sales Segment Forecasts for 100 Abused Drug, Cancer Diagnostic, Endocrine, Immunoprotein, TDM, and Special Chemistry Tests - L

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Veterinary Services

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China Genetic Testing Market: Industry Trends, Share, Size, Growth, Opportunity and Forecast 2021-2026

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Conclusion

In this study, we present primary hOM cells as a novel cellular model to interrogate air pollutant effects. We demonstrate that exposure to urban PM of different class sizes leads to a mild inflammatory response, increased oxidative stress and mitochondrial dysfunction. Specifically, cellular respiration and mitochondrial ROS are shown to be implicated in mitochondrial dysfunction. In addition, exposure to PM resulted in alteration to cytoplasmic and mitochondria-targeted transcripts associated with apoptosis and extracellular matrix organization which can be applied to early biomarker discovery in future air pollution studies. Further investigation of mitochondria targeted NPTX1 revealed its potential role in protection against PM exposure. Future studies may further dissect the interactome of NPTX1 in mitochondrial function, given that NPTX1 has been implicated in multiple age-related diseases associated with air pollution exposure.


North America HealthCare IT Market Outlook to 2016

NEW YORK , Oct. 10, 2011 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue:

North America HealthCare IT Market Outlook to 2016

GlobalData's new report, "North America HealthCare IT Market Outlook to 2016" provides key market data on the North America HealthCare IT market – United States and Canada . The report provides value (USD million) data for all the market categories – Hospital Information Systems and Medical Imaging Information Systems The report also provides company shares and distribution shares data for each of the aforementioned market categories. The report is supplemented with global corporate-level profiles of the key market participants.

This report is built using data and information sourced from proprietary databases, primary and secondary research and in-house analysis by GlobalData's team of industry experts.

- Countries covered include United States and Canada .

- Market size and company share data for HealthCare IT market categories – Hospital Information Systems and Medical Imaging Information Systems

- Annualized market revenues (USD million) data for each of the market categories in each of the country. Data from 2002 to 2009, forecast forward for 7 years to 2016.

- 2009 company shares and distribution shares data for each of the market categories and countries.

- Global corporate-level profiles of key companies operating within the North America HealthCare IT market.

- Key players covered include GE Healthcare, McKesson Corporation, Siemens Healthcare, Cerner Corporation, Eclipsys Corporation, Philips Healthcare, FUJIFILM Holdings Corporation, Allscripts-Misys Healthcare Solutions, Inc. Medical Information Technology, Inc, Agfa-Gevaert N.V., Picis, Inc and Carestream Health, Inc. / Kodak Health Group.

- Develop business strategies by identifying the key market categories and segments poised for strong growth.

- Develop market-entry and market expansion strategies.

- Design competition strategies by identifying who-stands-where in the North America HealthCare IT competitive landscape.

- Develop capital investment strategies by identifying the key market segments expected to register strong growth in the near future.

- What are the key distribution channels and what's the most preferred mode of product distribution – Identify, understand and capitalize.

2.1 What is This Report About? 13

3 HealthCare IT in North America 14

3.1 HealthCare IT Cross Country Comparison, Revenue ($m), 2002-2016 14

3.2 Healthcare IT, North America , Overall Revenue ($m), 2002-2016 15

3.3 Healthcare IT, North America , Company share (2008-2009) 20

4 HealthCare IT In United States 22

4.1 Healthcare IT, United States , Overall Revenue ($m), 2002-2016 22

4.2 HealthCare IT, United States , Distribution Share (2008-2009) 28

4.2.1 Hospital Information Systems, United States , Distribution Share (2008-2009) 28

4.2.2 Medical Imaging Information Systems, United States , Distribution Share (2008-2009) 28

4.3 HealthCare IT, United States , Company Share (2008-2009) 29

4.3.1 Healthcare IT, United States , Company Share (2008-2009) 29

4.3.2 Hospital Information Systems, United States , Company Share (2008-2009) 31

4.3.3 Medical Imaging Information Systems, United States , Company Share (2008-2009) 33

5 HealthCare IT In Canada 35

5.1 Healthcare IT, Canada , Overall Revenue ($m), 2002-2016 35

5.2 HealthCare IT, Canada , Distribution Share (2008-2009) 41

5.2.1 Hospital Information Systems, Canada , Distribution Share (2008-2009) 41

5.2.2 Medical Imaging Information Systems, Canada , Distribution Share (2008-2009) 41

5.3 HealthCare IT, Canada , Company Share (2008-2009) 42

5.3.1 Healthcare IT, Canada , Company Share (2008-2009) 42

5.3.2 Hospital Information Systems, Canada , Company Share (2008-2009) 44

5.3.3 Medical Imaging Information Systems, Canada , Company Share (2008-2009) 46

6 Overview of Key Companies in North America HealthCare IT Market 48

6.1.2 Share in the North America HealthCare IT Market 48

6.2 McKesson Corporation 49

6.2.2 Share in the North America HealthCare IT Market 49

6.3.2 Share in the North America HealthCare IT Market 50

6.4.2 Share in the North America HealthCare IT Market 51

6.5 Eclipsys Corporation 52

6.5.2 Share in the North America HealthCare IT Market 52

6.6.2 Share in the North America HealthCare IT Market 53

6.7 FUJIFILM Holdings Corporation 54

6.8 Allscripts-Misys Healthcare Solutions, Inc. 54

6.9 Medical Information Technology, Inc. 54

6.12 Carestream Health, Inc. 55

6.13 CompuGroup Medical AG. 55

7 HealthCare IT Market Pipeline Products 58

8 Financial Deals Landscape 59

8.1.1 Allscripts-Misys Healthcare Solutions Completes Merger with Eclipsys 59

8.1.2 maxIT Healthcare To Merge With Ingenuity Solutions Group 62

8.1.3 Accelrys Completes Merger With Symyx Technologies 63

8.2.1 MedLink International Acquires MedAppz 66

8.2.2 International Merchant Advisors To Acquire Good Health Network 67

8.2.3 The ConJoin Group Acquires PHNS 68

8.2.4 Omnicell Acquires Pandora Data Systems 69

8.2.5 Conifer Health Solutions Acquires MediHealth Outsourcing 70

8.2.6 Hyland Software Acquires The CSC Group 71

8.2.7 Ingenix To Acquire A-Life Medical 72

8.2.8 Covisint Acquires DocSite 73

8.2.9 RadNet To Acquire eRAD 74

8.2.10 Tricom Infotech To Acquire GTESS 75

8.2.11 PracticeMax Acquires Medinomics 76

8.2.12 Emdeon Acquires Chamberlin Edmonds & Associates 77

8.2.13 Ventana Medical Systems To Acquire BioImagene 79

8.2.14 WinSonic Digital Media Group Acquires VIPMEDRX 80

8.2.15 Ingenix Acquires Axolotl 81

8.2.16 Smartronix Acquires Cogon Systems 82

8.2.17 Orion Healthcare Ventures Acquires Aspyra 83

8.2.18 MedLink International Completes Acquisition Of Health Informatics 84

8.2.19 National Research Acquires Outcome Concept Systems 85

8.2.20 VHGI Holdings Completes Sale Of Medical Office Software To Private Company 86

8.2.21 Eyefinity/OfficeMate Acquires AcuityLogic 87

8.2.22 Cegedim Acquires Pulse Systems 88

8.2.23 Ingenix To Acquire Picis 89

8.3.1 Voxiva Enters Into An Agreement With PositiveID 90

8.3.2 MedInformatix Enters Into An Agreement With PhoneTree 91

8.3.3 ChartWise Medical Systems Enters Into An Agreement With 3M Health Information Systems 92

8.3.4 SRSsoft Enters Into An Agreement With Medstrat 93

8.3.5 Novadaq Technologies Enters Into Co-Marketing Agreement With LifeCell 94

8.3.6 Angeion Enters Into An Agreement With Data Innovations 95

8.3.7 DST Health Solutions Enters Into An Agreement With Health Data Vision 96

8.3.8 Omnicell Enters Into An Agreement With Sentry Data Systems 97

8.3.9 GE Healthcare And Intel To Form Joint Venture 98

8.3.10 MinuteClinic Enters Into An Agreement With St. Vincent's HealthCare 99

8.3.11 Intelerad Medical Systems Enters Into An Agreement With Fovia 100

8.3.12 Mediware Information Systems Enters Into Distribution Agreement With Unibased Systems Architecture 101

8.3.13 Kareo Enters Into An Agreement With Practice Fusion 102

8.3.14 Patient Access Solutions Enters Into An Agreement With MedLink International 103

8.3.15 IntrinsiQ Enters Into An Agreement With Allscripts 104

8.3.16 DigitalPersona Enters Into An Agreement With ScriptRx 105

8.3.17 Medidata Solutions Enters Into An Agreement With Aris Global 106

8.3.18 IntrinsiQ Enters Into An Agreement With eClinicalWorks 107

8.3.19 RaySearch Laboratories Expands Licensing Agreement With Varian Medical Systems 108

8.3.20 MedLink International Enters Into An Agreement With iMedicor 109

8.3.21 Carl Zeiss Vision Enters Into An Agreement With Eyemaginations 110

9 Recent Developments 111

9.1 Strategy And Business Planning 111

9.1.1 Nov 10, 2010: CardioComm Solutions Opens New Coordinating Centre In Ontario 111

9.1.2 Nov 01, 2010: Synteract Triples Space In North Carolina Office To Accommodate Growth 111

9.1.3 Oct 29, 2010: LitePoint Joins Continua Health Alliance 112

9.1.4 Oct 27, 2010: Welch Allyn EHR Prep-Select Service Becomes Integral Part Of Ohio Health Information Partnership's EHR Adoption Program 112

9.1.5 Oct 05, 2010: MedPlus, HP Partner To Facilitate EHR Adoption For Physician Practices Nationwide 113

9.1.6 Oct 05, 2010: MEDITECH To Open New Office In Freetown, Massachussetts 114

9.1.7 Sep 23, 2010: HLI And HCL Technologies Partner To Offer ICD-10 Conversion Solution 114

9.1.8 Sep 09, 2010: MediCROstar Joins Medidata Solutions' Channel Partner Program 115

9.1.9 Sep 07, 2010: Welch Allyn, ASGE Partner To Increase EHR Usage 116

9.1.10 Aug 16, 2010 : iSALUS Forms Strategic Partnership With IMS To Provide EMR-EHR Software System 117

9.1.11 Aug 16, 2010 : Welch Allyn, ACC Partner To Aid Members In EHR Selection Process 117

9.1.12 Aug 13, 2010 : Thermo Fisher To Shut Down Rhode Island Facility By June 2011 118

9.1.13 Aug 12, 2010 : Siemens Partners With ExitCare To Deliver Patient Education Services To Health IT Customers 118

9.1.14 Aug 10, 2010 : Wellstar To Implement TMI Virtual Cloud Data System 119

9.1.15 Aug 10, 2010 : iMedicor, USA MCO Announce Strategic Alliance To Create NHCN 119

9.1.16 Aug 04, 2010 : Varian Medical Systems Expands Clinical Consulting Services To Cancer Care Centers Worldwide 120

9.1.17 Jul 27, 2010 : BioImagene Collaborates With Ten Academic Medical Centers To Advance Digital Pathology Solutions 121

9.1.18 Jul 26, 2010 : National Comprehensive Cancer Network (NCCN) And Proventys Collaborate To Enhance Quality And Efficiency In Cancer Care 121

9.1.19 Jul 22, 2010 : St Clair Hospital, PHI And GE Healthcare Collaborate To Create Integrated HER 122

9.1.20 Jul 14, 2010 : GE Healthcare To Shut Down Two Offices In Waukesha 123

9.1.21 Jun 29, 2010 : SRI International, Stanford University School Of Medicine Establish MISTRAL Collaborative To Innovate Medical Device Development 123

9.1.22 Jun 17, 2010 : Baxter Opens New Research & Development Facility In Alliance Park, Belgium 124

9.1.23 May 19, 2010 : Philips And Project HOPE To Improve Access To Care Through Telehealth In New Mexico 125

9.1.24 May 17, 2010 : Helicos BioSciences Announces Strategic Focus On Diagnostics Markets And Operational Restructuring 125

9.1.25 May 13, 2010 : Parexel Opens Two More New Offices In China 126

9.1.26 May 10, 2010 : Honeywell HomMed And eDevice Expand Connectivity Solutions For Telehealth 126

9.1.27 Apr 27, 2010 : Cambridge University Hospitals NHS Trust Embarks On Proactive Pathology Results Pilot With Carefx 127

9.1.28 Apr 27, 2010 : Secure eHealth Collaborates With Healthpoints Project For Diabetic Disease Management 128

9.1.29 Apr 20, 2010 : Siemens Opens National Customer Service Headquarters For 24x7 Service And Support 128

9.1.30 Apr 12, 2010 : Mediware Announces The Creation Of A New Business Unit 129

9.2 Government and Public Interest 130

9.2.1 Nov 12, 2010: MedInformatix' EHR Solutions Achieve ONC Meaningful Use Certification 130

9.2.2 Nov 10, 2010: CCHIT To Launch Customized EHR Certification Program For Hospitals 131

9.2.3 Nov 08, 2010: XStor Medical Achieves ISO 13485 Certification 132

9.2.4 Nov 04, 2010: Vital Images Wins Tekne Award In 'IT-Software & Hardware, Communications and Infrastructure' Category 132

9.2.5 Nov 03, 2010: HHS Announces New Federal Support For States To Develop And Upgrade Medicaid IT Systems And Systems For Enrollment In State Exchanges 133

9.2.6 Oct 26, 2010: New York State Sets Plan To Create Electronic Medical Records Network 134

9.2.7 Oct 19, 2010: HITSE Announces Speakers And Session Updates For Upcoming HITSE New England Conference 135

9.2.8 Oct 04, 2010: New Study Shows Telemedicine Works To Effectively Identify Heart Problems In Children Far From A Specialized Medical Center 136

9.2.9 Oct 01, 2010: CCHIT Certifies 33 EHR Products Under ONC-ATCB Program 137

9.2.10 Sep 29, 2010 : IOM To Study Best Policies And Practices For Improving Health Care Safety HIT 137

9.2.11 Sep 21, 2010 : Almacs Clinical Technologies Clears Joint GCP-GMP MHRA Inspection 138

9.2.12 Sep 17, 2010 : Health IT Policy Committee Focuses On Meaningful Use Stage 2 And Accessibility: HIMSS 139

9.2.13 Sep 15, 2010 : HIMSS Announces Six Winners Of 2010 HIMSS Davies Awards For Delivering Quality Care To Patients Through HIT, Specifically EHRs 139

9.2.14 Sep 01, 2010 : ChartLogic Applies To Drummond For Meaningful Use Certification 140

9.2.15 Aug 30, 2010 : ONC Names CCHIT, Drummond As EHR Certifiers 141

9.2.16 Aug 23, 2010 : ASIR Algorithm Reduces Radiation Dose In CT Angiography 142

9.2.17 Aug 20, 2010 : Electronic Tracking System Can Improve Follow-Up After An Abnormal Pap Test: BUSM 142

9.2.18 Aug 17, 2010 : California Launches Statewide Telehealth Network In Sacramento 143

9.2.19 Aug 10, 2010 : Vital Images Earn Re-Certification From TSIA 144

9.2.20 Aug 06, 2010 : Phase Forward Announces US Department Of Justice Clearance 145

9.2.21 Aug 05, 2010 : ABMS To Develop Physician Assessments Related To HIT As Part Of ABMS Maintenance Of Certification Program 145

9.2.22 Aug 05, 2010 : Accelerating Electronic Health Records Adoption And Meaningful Use: ONC, CMS 146

9.2.23 Aug 03, 2010 : Continua Health Alliance Commends FCC And FDA For Working To Streamline Wireless Medical Technology Review Process 147

9.3.1 Sep 09, 2010: Affinity Health System Selects GE Healthcare's Centricity EMR 148

9.3.2 Aug 26, 2010: Agfa HealthCare Launches IMPAX HeartStation Solution For ECG Analysis In Europe 148

9.3.3 Aug 25, 2010: Phelps County Regional Medical Center Selects Wolters Kluwer Health's ProVation Medical Software For Gastroenterology Procedure Documentation And Coding 149

9.3.4 Aug 17, 2010: Oridion To Present Results Of New Study For Integrated Pulmonary Index At ATACCC Conference 149

9.3.5 Aug 11, 2010: Viatronix Announces Latest Release Of V3D-Colon Software Now Offering First 510(k) Approved Colon CAD For US Market 150

9.3.6 Aug 04, 2010: Marion General Hospital Selects GE Healthcare's Centricity Enterprise EMR 150

9.3.7 Aug 03, 2010: InHealth Imaging Selects Intelerad's Fully Integrated IntelePACS Solution 150

9.3.8 Aug 02, 2010: ALR Technologies Publishes Clinical Trial Results Of ALRT Health-e-Connect System In Diabetes Care August, 2010 151

9.3.9 Jul 28, 2010: NDSsi Launches Next-Generation ConnectOR G2 Informatics Platform 151

9.3.10 Jul 26, 2010 : ALR Technologies Announces FDA 510(k) Filing For Health-e-Connect (HeC) System For Diabetes Patients 152

9.3.11 Jul 20, 2010 : IMI Selects Intelerad's IntelePACS Breast Imaging Solution 152

9.3.12 Jul 19, 2010 : ECMC Selects Allscripts Electronic Health Record 152

9.3.13 Jul 19, 2010 : MedWest Selects Allscripts Electronic Health Record And Practice Management For Employed Physicians 153

9.3.14 Jul 14, 2010 : Shoreline Surgery Center Selects ProVation Medical Software For Gastroenterology Procedure Documentation And Coding 154

9.3.15 Jul 14, 2010 : Varian To Showcase Brachytherapy Planning System At Annual Meeting Of American Association Of Physicists In Medicine 154

9.3.16 Jul 13, 2010 : SunTech Medical Launches AccuWin Pro v3 Software With Pediatric ABPM Interpretation As Primary Feature 155

9.3.17 Jul 08, 2010 : CPMG Selects Allscripts Electronic Health Record For Physicians Alliance 155

9.3.18 Jun 07, 2010 : UBMD Selects Allscripts Electronic Health Record 156

9.3.19 Jun 03, 2010 : Varian Receives Surescripts E-Prescribing Certification For ARIA Oncology Information System 157

9.3.20 Jun 01, 2010 : Healthcare South Selects Allscripts Electronic Health Record And Practice Management For Primary Care Group 157

9.3.21 May 26, 2010 : US Oncology To Demonstrate iKnowMed EHR At 2010 ASCO Annual Meeting 158

9.3.22 May 25, 2010 : St. Jude Enrolls First Patient In FAME II Clinical Trial To Study Use Of Fractional Flow Reserve 159

9.3.23 May 12, 2010 : Southlake Clinic Selects Wolters Kluwer Health's ProVation MD Software And ProVation HER 160

9.3.24 May 10, 2010 : St. Jude Medical Launches Wireless USB Adaptor For [email protected] Transmitter 160

9.3.25 May 06, 2010 : The Jackson Clinic Selects Allscripts Electronic Health Record 161

9.3.26 May 04, 2010 : New York-Based Orthopedic And Pain Management Practices To Deploy Allscripts For Electronic Health Record And Practice Management 161

9.3.27 Apr 29, 2010 : Medical & Surgical Clinic Of Irving Selects Allscripts For Electronic Health Record 162

9.3.28 Apr 13, 2010 : Mesquite Surgery Center Installs Wolters Kluwer Health's ProVation MD And ProVation EHR 162

9.3.29 Apr 07, 2010 : Sarasota Memorial Hospital Installs Wolters Kluwer Health's ProVation Medical Software 163

9.3.30 Apr 06, 2010 : AnMed Health Installs Allscripts HER 163

9.3.31 Apr 05, 2010 : FiatLux Imaging Announces Extended Free Availability Of Visualize FREE Software 164

9.3.32 Apr 01, 2010 : Capital Region Orthopaedics Installs Allscripts Electronic Health Record And Practice Management Solution 164

9.3.33 Apr 01, 2010 : Masimo Announces Installation Of Masimo Patient SafetyNet System At John Hunter Children's Hospital 165

10.1 Definitions of Markets Covered in the Report 167

10.2 Research Methodology 168

10.3 Secondary Research 168

10.8 GlobalData Consulting 170

10.9 Currency Conversion 170

10.11 Disclaimer 1711.1 List of Tables

Table 1: HealthCare IT, Cross Country Comparison, Revenue ($m), 2002-2016 14

Table 2: Healthcare IT, North America , Overall Revenue ($m), 2002-2016 15

Table 3: Healthcare IT, North America , Overall Revenue ($m), Historic, 2002-2009 17

Table 4: Healthcare IT, North America , Overall Revenue ($m), Forecast, 2009-2016 19

Table 5: Healthcare IT, North America , Company share by Revenue ($m), 2008-2009 21

Table 6: Healthcare IT, United States , Overall Revenue ($m), 2002-2016 23

Table 7: Healthcare IT, United States , Overall Revenue ($m), Historic, 2002-2009 25

Table 8: Healthcare IT, United States , Overall Revenue ($m), Forecast, 2009-2016 27

Table 9: Hospital Information Systems, United States , Distribution Share by Revenue ($m), 2008-2009 28

Table 10: Medical Imaging Information Systems, United States , Distribution Share by Revenue ($m), 2008-2009 28

Table 11: Healthcare IT, United States , Company Share by Revenue ($m), 2008-2009 30

Table 12: Hospital Information Systems, United States , Company Share by Revenue ($m), 2008-2009 32

Table 13: Medical Imaging Information Systems, United States , Company Share by Revenue ($m), 2008-2009 34

Table 14: Healthcare IT, Canada , Overall Revenue ($m), 2002-2016 36

Table 15: Healthcare IT, Canada , Overall Revenue ($m), Historic, 2002-2009 38

Table 16: Healthcare IT, Canada , Overall Revenue ($m), Forecast, 2009-2016 40

Table 17: Hospital Information Systems, Canada , Distribution Share by Revenue ($m), 2008-2009 41

Table 18: Medical Imaging Information Systems, Canada , Distribution Share by Revenue ($m), 2008-2009 41

Table 19: Healthcare IT, Canada , Company Share by Revenue ($m), 2008-2009 43

Table 20: Hospital Information Systems, Canada , Company Share by Revenue ($m), 2008-2009 45

Table 21: Medical Imaging Information Systems, Canada , Company Share by Revenue ($m), 2008-2009 47

Table 22: HealthCare IT Market Pipeline Products 58

Table 23: Allscripts-Misys Healthcare Solutions Completes Merger With Eclipsys 59

Table 24: maxIT Healthcare To Merge With Ingenuity Solutions Group 62

Table 25: Accelrys Completes Merger With Symyx Technologies 63

Table 26: MedLink International Acquires MedAppz 66

Table 27: International Merchant Advisors To Acquire Good Health Network 67

Table 28: The ConJoin Group Acquires PHNS 68

Table 29: Omnicell Acquires Pandora Data Systems 69

Table 30: Conifer Health Solutions Acquires MediHealth Outsourcing 70

Table 31: Hyland Software Acquires The CSC Group 71

Table 32: Ingenix To Acquire A-Life Medical 72

Table 33: Covisint Acquires DocSite 73

Table 34: RadNet To Acquire eRAD 74

Table 35: Tricom Infotech To Acquire GTESS 75

Table 36: PracticeMax Acquires Medinomics 76

Table 37: Emdeon Acquires Chamberlin Edmonds & Associates 77

Table 38: Ventana Medical Systems To Acquire BioImagene 79

Table 39: WinSonic Digital Media Group Acquires VIPMEDRX 80

Table 40: Ingenix Acquires Axolotl 81

Table 41: Smartronix Acquires Cogon Systems 82

Table 42: Orion Healthcare Ventures Acquires Aspyra 83

Table 43: MedLink International Completes Acquisition Of Health Informatics 84

Table 44: National Research Acquires Outcome Concept Systems 85

Table 45: VHGI Holdings Completes Sale Of Medical Office Software To Private Company 86

Table 46: Eyefinity/OfficeMate Acquires AcuityLogic 87

Table 47: Cegedim Acquires Pulse Systems 88

Table 48: Ingenix To Acquire Picis 89

Table 49: Voxiva Enters Into An Agreement With PositiveID 90

Table 50: MedInformatix Enters Into An Agreement With PhoneTree 91

Table 51: ChartWise Medical Systems Enters Into An Agreement With 3M Health Information Systems 92

Table 52: SRSsoft Enters Into An Agreement With Medstrat 93

Table 53: Novadaq Technologies Enters Into Co-Marketing Agreement With LifeCell 94

Table 54: Angeion Enters Into An Agreement With Data Innovations 95

Table 55: DST Health Solutions Enters Into An Agreement With Health Data Vision 96

Table 56: Omnicell Enters Into An Agreement With Sentry Data Systems 97

Table 57: GE Healthcare And Intel To Form Joint Venture 98

Table 58: MinuteClinic Enters Into An Agreement With St. Vincent's HealthCare 99

Table 59: Intelerad Medical Systems Enters Into An Agreement With Fovia 100

Table 60: Mediware Information Systems Enters Into Distribution Agreement With Unibased Systems Architecture 101

Table 61: Kareo Enters Into An Agreement With Practice Fusion 102

Table 62: Patient Access Solutions Enters Into An Agreement With MedLink International 103

Table 63: IntrinsiQ Enters Into An Agreement With Allscripts 104

Table 64: DigitalPersona Enters Into An Agreement With ScriptRx 105

Table 65: Medidata Solutions Enters Into An Agreement With Aris Global 106

Table 66: IntrinsiQ Enters Into An Agreement With eClinicalWorks 107

Table 67: RaySearch Laboratories Expands Licensing Agreement With Varian Medical Systems 108

Table 68: MedLink International Enters Into An Agreement With iMedicor 109

Table 69: Carl Zeiss Vision Enters Into An Agreement With Eyemaginations 110

Table 70: USD to Local Currency, North America , Average Exchange Rate 2002-2009 1701.2 List of Figures

Figure 1: HealthCare IT, Cross Country Comparison, Revenue ($m), 2002-2016 14

Figure 2: Healthcare IT, North America , Overall Revenue ($m), 2002-2016 15

Figure 3: Healthcare IT, North America , Overall Revenue ($m), Historic, 2002-2009 16

Figure 4: Healthcare IT, North America , Overall Revenue ($m), Forecast, 2009-2016 18

Figure 5: Healthcare IT, North America , Company share (%), 2009 20

Figure 6: Healthcare IT, United States , Overall Revenue ($m), 2002-2016 22

Figure 7: Healthcare IT, United States , Overall Revenue ($m), Historic, 2002-2009 24

Figure 8: Healthcare IT, United States , Overall Revenue ($m), Forecast, 2009-2016 26

Figure 9: Healthcare IT, United States , Company Share (%), 2009 29

Figure 10: Hospital Information Systems, United States , Company Share (%), 2009 31

Figure 11: Medical Imaging Information Systems, United States , Company Share (%), 2009 33

Figure 12: Healthcare IT, Canada , Overall Revenue ($m), 2002-2016 35

Figure 13: Healthcare IT, Canada , Overall Revenue ($m), Historic, 2002-2009 37

Figure 14: Healthcare IT, Canada , Overall Revenue ($m), Forecast, 2009-2016 39

Figure 15: Healthcare IT, Canada , Company Share (%), 2009 42

Figure 16: Hospital Information Systems, Canada , Company Share (%), 2009 44

Figure 17: Medical Imaging Information Systems, Canada , Company Share (%), 2009 46

Figure 18: GE Healthcare, Company Share (%), North America HealthCare IT Market, 2009 48

Figure 19: McKesson Corporation, Company Share (%), North America HealthCare IT Market, 2009 49

Figure 20: Siemens Healthcare, Company Share (%), North America HealthCare IT Market, 2009 50

Figure 21: Cerner Corporation, Company Share (%), North America HealthCare IT Market, 2009 51

Figure 22: Eclipsys Corporation, Company Share (%), North America HealthCare IT Market, 2009 52

Figure 23: Philips Healthcare, Company Share (%), North America HealthCare IT Market, 2009 53

FUJIFILM Holdings Corporation

Allscripts-Misys Healthcare Solutions, Inc.

Medical Information Technology, Inc.

CONTACT
Nicolas Bombourg
Reportlinker
Email: [email protected]
US: (805)652-2626
Intl: +1 805-652-2626


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Summaries Of The News:

Over the course of the year, the number of people signed up and paying premiums on exchange plans went down 25 percent, from 11.7 million to 8.8 million. In other health law news, a few of the troubled insurance cooperatives could turn profits in 2016. And Blue Cross and Blue Shield of Illinois hopes for a financial turnaround after last year's flop.

The Associated Press: Obama Health Law Missed 2015 Enrollment Target
Last year's final enrollment numbers under President Barack Obama's health care law fell just short of a target the administration had set, the government reported Friday. The report from the Health and Human Services Department said about 8.8 million consumers were still signed up and paying premiums at the end of last year. HHS Secretary Sylvia M. Burwell had set a goal of having 9.1 million customers by then. So the administration didn't miss its target by much — about 3 percent. (Alonso-Zaldivar, 3/11)

The Associated Press: ACA Co-Ops Lose Millions In 2015 Some Expect 2016 Profits
The Affordable Care Act's health insurance co-ops absorbed deep financial losses last year, and 2016 is shaping up to be a make-or-break year for these nonprofit alternatives to traditional insurers. Officially called Consumer Operated and Oriented Plans, these still-fledgling insurers were devised during the ACA's creation to inject competition into insurance markets. But they have struggled from the start to build a customer base from scratch and deal with higher-than-expected expenses, among other problems. (3/11)

The Chicago Tribune: Blue Cross Parent Lost $1.5B On Individual Health Plans Last Year
Year 2 of the Affordable Care Act was another financial flop for the Chicago-based parent of Blue Cross and Blue Shield of Illinois but hints of a turnaround are emerging. Health Care Service Corp.'s financial losses in its individual business, which includes ACA plans, worsened in 2015. The company, which owns Blue Cross affiliates in Illinois and four other states, said it lost $1.5 billion in its individual business, up from $767 million in 2014, the first year of the health law's state exchanges for buying coverage. (Sachdev, 3/11)

A spokesman for Bernie Sanders released a photo and video clip from 1993 showing the candidate standing directly behind Hillary Clinton at an event to promote health care reform.

The Huffington Post: Sanders Fires Back At Clinton For Distorting His Health Care Record
In the latest round of policy battles between Democratic presidential opponents Hillary Clinton and Sen. Bernie Sanders (I-Vt.), Clinton diminished Sanders’ record on healthcare on Saturday, raising the ire of the Sanders campaign. In pledging to take on the power of the healthcare and pharmaceutical industries if she becomes president, Clinton accused Sanders of being absent in her fight for health care reform in the 1990s. (Fang, 3/13)

In other news, prescription drug costs have become a hot topic with 2016 voters —

Los Angeles Times: Voter Anger Over Surging Prescription Drug Costs Has Generated A Campaign Issue
[The] concern about the cost of prescription drugs has emerged as a big issue in the presidential campaign, prompting candidates in both parties to sharpen their rhetoric against pharmaceutical companies and put curbing drug prices at the center of their healthcare plans. The message is particularly resonant here in Florida, which holds its primary Tuesday and where people over 60 make up more than a third of registered voters. At the Democratic debate in Miami on Wednesday, Sen. Bernie Sanders repeatedly castigated drug companies for “ripping off” the American public. Hillary Clinton has vowed to rein in drug prices and is running an ad in Florida specifically focusing on the “predatory” pricing of one embattled pharmaceutical company, Valeant. (Mason, 3/11)

Patients are left to decide what to do when doctors can't reach a consensus on a course of action when genetic tests turn up a higher risk for diseases like breast cancer.

The New York Times: When Gene Tests For Breast Cancer Reveal Grim Data But No Guidance
At a time when genetic testing and genetically personalized treatments for cancer are proliferating, buoyed by new resources like President Obama’s $215 million personalized medicine initiative, women with breast cancer are facing a frustrating reality: The genetic data is there, but in many cases, doctors do not know what to do with it. . Doctors have long been tantalized by a future in which powerful methods of genetic testing would allow treatments to be tailored to a patient’s genetic makeup. Today, in breast cancer treatment, testing of tumors and healthy cells to look for mutations has become standard. But . “our ability to sequence genes has gotten ahead of our ability to know what it means,” said Eric P. Winer, the director of the breast oncology program at Harvard’s Dana-Farber Cancer Institute. (Kolata, 3/11)

PBS NewsHour and The Fiscal Times report on the challenges consumers face through these types of health expenses.

PBS NewsHour: Surprise Medical Bills Are Stacking Up For Many Adults
One in three American adults who have private health insurance coverage are hit with surprise medical bills they thought were covered by insurance, which can range from a few hundreds dollars to tens of thousands for an operation. Time Magazine's Haley Sweetland Edwards joins Hari Sreenivasan to discuss.

The Fiscal Times: Long-Term Care: The Cost Challenge That Scares The Government Most
For years, federal and state governments have shied away from the problem of providing long-term care for ailing seniors – and for good reason. While mounting costs of Social Security, prescription drugs and federal health care programs get a lot of attention, the staggering costs of providing community based social services and nursing home facilities and in-home care to seniors are draining the savings of average Americans and posing frightening long-term fiscal challenges for government officials. (Pianin, 3/13)

As they gain prominence, wearable devices -- and the health data that comes with them -- are provoking questions about how much information employers can collect and just what they can do with it. In other technology news, New York is going all digital when it comes to writing prescriptions.

The Wall Street Journal: As Wearables In Workplace Spread, So Do Legal Concerns
Wearable devices, like the Fitbits and Apple Watches sported by runners and early adopters, are fast becoming tools in the workplace. These devices offer employers new ways to measure productivity and safety, and give insurers the ability to track workers’ health indicators and habits. For companies with large workforces, the prospect of tracking people’s whereabouts and productivity can be welcome. But collecting data on employees’ health and their physical movement can trigger a host of potential ethical and legal headaches for employers. (Haggin, 3/13)

The New York Times: New York To Discard Prescription Pads, And Doctors’ Handwriting, In Digital Shift
Starting on March 27, the way prescriptions are written in New York State will change. Gone will be doctors’ prescription pads and famously bad handwriting. In their place: pointing and clicking, as prescriptions are created electronically and zapped straight to pharmacies in all but the most exceptional circumstances. New York is the first state to require that all prescriptions be created electronically and to back up that mandate with penalties, including fines and imprisonment, for physicians who fail to comply. Minnesota has a law requiring electronic prescribing but does not penalize doctors who cling to pen and paper. (Otterman, 3/14)

Proponents say the facilities save lives and make it easier for users to get treatment. In other news, a growing number of states are passing legislation to address opioid addiction, PBS NewsHour looks at the growing number of babies being born going through withdrawal, and a small town's fight against the epidemic is representative of the crisis spreading across the country.

Stateline: Are State-Sanctioned Heroin Shooting Galleries A Good Idea?
A bustling economy. Record-low unemployment. A ballooning heroin problem. That’s how Mayor Svante Myrick describes Ithaca, New York, where he hopes to open the nation’s first safe injection facility — a place where heroin users could shoot their illegal drugs under medical supervision and without fear of arrest. His proposal, part of a plan to address drug abuse in the 31,000-person college town in central New York, is not a novel idea. Safe injection sites, which also connect clients to treatment programs and offer emergency care to reverse overdoses, exist in 27 cities in other parts of the world. Some have been around for decades. (Breitenbach, 3/11)

The New York Times: States Move To Control How Painkillers Are Prescribed
A growing number of states, alarmed by the rising death toll from prescription painkillers and frustrated by a lack of federal action, are moving to limit how these drugs are prescribed. On Thursday, Massachusetts lawmakers passed a bill expected to be signed next week that would sharply restrict the number of pain pills a doctor can prescribe after surgery or an injury to a seven-day supply. Officials in Vermont and Maine are considering similar actions, and governors across the country are set to meet this summer to develop a broad approach that could reduce the use of painkillers like OxyContin, Percocet and Vicodin. (Meier and Tavernise, 3/11)

PBS NewsHour: Detoxing After Delivery: When Babies Are Born Withdrawing From Opioids
The number of American babies born going through withdrawal from prescription painkillers and heroin used by their mothers during pregnancy, a condition called Neonatal Abstinence Syndrome, increased fivefold between 2000 and 2012. (3/12)

NPR: A Small Town Wonders What To Do When Heroin Is 'Everywhere'
The epidemic of opioid abuse that's swept the U.S. has left virtually no community unscathed, from big cities to tiny towns. In fact, drug overdose is now the leading cause of injury death in this country: more than gun deaths more than car crashes. There were more than 47,000 drug overdose deaths in the U.S. in 2014, according to the Centers for Disease Control and Prevention. That includes unintentional overdoses and suicides. More than half of those were from opioids, including painkillers and heroin. (Block, 3/12)

Also, the federal government gives money to two states to fund their efforts targeting opioid addiction —

The Boston Globe: $6.8 Million In New Federal Money Coming To Mass. For Drug Treatment
Twenty community health centers in Massachusetts will share $6.8 million in grants to expand substance abuse services, particularly treatment of opioid addiction, the US Health and Human Services Department announced Friday. (Freyer, 3/11)

The Seattle Times: Heroin Epidemic, Painkiller Abuse Targeted By New Federal Money For Treatment
Community health centers in Washington state have been awarded nearly $3 million of some $94 million in federal funding to fight opioid abuse and addiction, health officials announced Friday. The money was allocated through the Affordable Care Act (ACA) to address the growing problem of addiction to opioids, including prescription painkillers and illicit drugs such as heroin. (Aleccia, 3/11)

The agency will make its final decision after it has given the public time to comment on the experiment but says it has concluded that the mosquitoes would not cause harm to the people or environment. In other Zika outbreak news, the CDC releases new guidance about how elevation affects risk of contracting the disease, and health officials confirm 201 cases in Puerto Rico.

The New York Times: Test Of Zika-Fighting Genetically Engineered Mosquitoes Gets Tentative F.D.A. Approval
The federal government on Friday moved to clear the way for the release of genetically engineered mosquitoes into the wild for the first time in the United States, tentatively approving a field test that might help slow the spread of the Zika virus. The genetically engineered insects, which contain a gene that will kill their offspring, have already shown effectiveness in small tests in Brazil and other countries in suppressing the populations of the mosquitoes that transmit both Zika and dengue fever. (Pollack, 3/11)

Reuters: FDA Says Engineered Anti-Zika Mosquito Environmentally Safe
U.S. health regulators said a genetically engineered mosquito being used in the fight against Zika will not have a significant impact on the environment, possibly paving the way for the technique to be used in the country. The self-limiting strain of the Aedes aegypti mosquito was developed by Oxitec, the U.K.-subsidiary of U.S. synthetic biology company Intrexon Corp. The male mosquitoes are modified so their offspring will die before reaching adulthood and being able to reproduce. (3/12)

The Washington Post: Want To Avoid Zika? Stay More Than A Mile Above Sea Level, CDC Says
The Centers for Disease Control and Prevention now says pregnant women can safely travel to Zika-affected countries if they stay at elevations higher than 6,562 feet, where they’ll find few mosquitoes that could spread the virus. But the agency’s revised travel advisory, released Friday, continues to recommend that trips to lower-elevation areas be avoided because the greater presence of mosquitos increases the risk of infection. (Sun, 3/11)

The Associated Press: Puerto Rico Reports 201 Confirmed Zika Cases
Puerto Rico’s Health Department is reporting 201 confirmed Zika cases amid warnings the U.S. territory could face an epidemic of the mosquito-borne virus. Officials said Friday that 21 of those cases involve pregnant women. This concerns health authorities because Zika may be linked to microcephaly, which causes babies to have unusually small heads and brain damage. The director of the U.S. Centers for Disease Control and Prevention visited the island on Tuesday as federal officials stepped up efforts to help prevent the spread of Zika in Puerto Rico. (3/11)

The legislation would ban abortion in cases where the fetus has a genetic abnormality and in cases based on gender, race or ancestry. Conservatives believe Gov. Mike Pence will sign it. Elsewhere, the Georgia House passes a measure to provide funding to "pregnancy resource centers" that discourage abortion.

The Associated Press: Indiana: Bill Banning Abortions For Genetic Causes Goes To Governor
Gov. Mike Pence stressed his anti-abortion convictions on Friday, leaving fellow conservatives to believe he will sign a measure making the state the second to ban abortion in cases in which a fetus has a genetic abnormality, such as Down syndrome. In addition, the bill would ban abortions because of race, gender or ancestry. Mr. Pence, a Republican, co-sponsored legislation as a member of the United States House in 2011 that would have prohibited abortions sought because of gender. (3/11)

The Associated Press: Grant Program For Anti-Abortion Centers Passes Georgia House
Georgia would provide state-funded grants to "pregnancy resource centers" that offer medical care, counseling and other services to pregnant women while discouraging abortion, under legislation that easily passed the state House on Friday. The state Senate approved the measure on party lines last month. Senators must agree to some minor changes before the proposal can head to Gov. Nathan Deal's desk. To be eligible, facilities cannot encourage or discuss abortions as an option or refer women to clinics that perform abortions, except when the mother's life is threatened. (3/11)

And Missouri's latest efforts to defund Planned Parenthood —

The Associated Press: Future Uncertain For Proposal To Defund Planned Parenthood
Missouri lawmakers' effort to strip Planned Parenthood of any state money faces an uncertain path forward. While the House passed a budget this week that bars any entity that provides or counsels a woman to get a non-emergency abortion from receiving Medicaid reimbursements, courts have blocked similar attempts in other states and the Senate's budget writers have so far declined to endorse the effort. (Aton, 3/12)

News outlets report on health issues in Michigan, Puerto Rico, Washington, Virginia, California, Illinois, Ohio and North Carolina.

The Associated Press: Gov. Snyder Calls For Investigation Of Health Department
Michigan Gov. Rick Snyder on Friday called for an investigation of how his health department handled an outbreak of Legionnaires’ disease in the Flint area as well as high lead levels among residents who were drinking tainted water from the Flint River. Snyder was briefed on an “internal review” of the Department of Health and Human Services and now wants the agency’s inspector general and Michigan’s auditor general to quickly launch a broader investigation, spokesman Ari Adler said. (White, 3/11)

Reuters: Michigan Auditors Will Probe State Health Agency On Flint Water
Michigan auditors will probe the state's Department of Health and Human Services over its handling of elevated lead levels in Flint drinking water and a rise in Legionnaire’s disease cases, Governor Rick Snyder said Friday. Snyder called for the state’s Auditor General and the health agency's inspector general to investigate the problems in Flint and surrounding Genesee County, and they agreed, the state said. (Shepardson and Klayman, 3/11)

NPR: SOS: Puerto Rico Is Losing Doctors, Leaving Patients Stranded
Puerto Rico is losing people. Due to a decade-long recession, more than 50,000 residents leave the U.S. territory each year—most for jobs and new lives on the mainland. This issue is especially affecting healthcare, where it's estimated that at least one doctor leaves Puerto Rico every day. The mass exodus of doctors is creating vacancies that are hard to fill and waiting lists for patient care. Dr. Antonio Peraza is among those doctors who recently left for the mainland. He specializes in internal medicine and for nearly 14 years, had a private practice in Bayamon, Puerto Rico. (Allen, 3/12)

The Seattle Times: Group Health Approves Acquisition By Kaiser Permanente
Rejecting critics and community concern, voting members of Seattle’s Group Health Cooperative have overwhelmingly agreed to join with the California health-care giant Kaiser Permanente. Voting 8,824 to 1,586 in mailed-in ballots, the members approved the move that essentially dissolves the iconic, home-grown cooperative, founded nearly 70 years ago with the mission of providing integrated health care and health coverage to Northwest residents. (Aleccia, 3/10)

The Washington Post: Virginia Lawmakers Wrap Up Session, Send $105 Billion Budget To Governor
Virginia lawmakers finished their work late Friday one day ahead of schedule and sent Gov. Terry McAuliffe (D) a budget that would give teachers raises and increase spending for education and economic development. . For the third straight year, the Republican-controlled General Assembly denied McAuliffe and Democrats expansion of Medicaid and rejected the governor’s plan to tax hospitals and use the revenue to fund the state’s share of the federal health-care program. “We don’t have any answer for the 400,000 Virginians who don’t have any health-care coverage,” Del. Marcus B. Simon (D-Fairfax) said. (Portnoy, 3/12)

The Associated Press: Money From Hospital Sale To Be Used For Health Initiatives
Money from the sale of the Indiana University LaPorte Hospital was used to create a nonprofit foundation that will focus on trying to improve the health of the northern Indiana county. A deal to sell an 80 percent stake in the hospital to Community Health Systems, a for-profit hospital system based in Franklin, Tennessee, was finalized Tuesday. IU Health will retain a 20 percent stake in the hospital. The deal also includes the 50-bed IU Health Starke Hospital in Knox. (3/13)

The Sacramento Bee: California Tobacco Bills Spurred Hardball Political Threats
Tobacco industry lobbyists threatened to scuttle unrelated ballot initiatives if California lawmakers passed sweeping anti-smoking measures, health advocates said on Friday. While lawmakers said bills now on Gov. Jerry Brown’s desk to raise the tobacco-buying age to 21 and to regulate electronic cigarettes as tobacco products drew fierce industry opposition, they characterized the effort as a hard-to-trace background campaign. Assembly Speaker-elect Anthony Rendon, D-Lakewood, last week told reporters lawmakers had received “threats involving electoral efforts.” (White, 3/11)

The Chicago Tribune: Doctor Given Prison For Taking Kickbacks To Prescribe Risky Drug
A Chicago doctor who was once the nation's most prolific prescriber of the risky antipsychotic drug clozapine was sentenced to nine months in prison Friday for taking cash, vacation trips and other kickbacks from the drug's manufacturers. Dr. Michael Reinstein, the subject of a 2009 Tribune-ProPublica joint investigation, admitted to pocketing nearly $600,000 in benefits over the years for prescribing various forms of clozapine, known as a risky drug of last resort, to hundreds of mentally ill patients in his care. (Meisner, 3/11)

The Associated Press: VA Makes Home Visits To Patients In Pilot Project
The Iraq vet fitted a blood-pressure wrap around the Vietnam vet's arm, checked the gauge and announced, "Nice blood pressure today. Right in the range we want." Andrew Bisbee, a former Army medic, then checked his patient's heart, throat and swollen feet. "I know I'm not a spring chicken anymore," said the patient, Gerald Bowles, 65, of Cleveland. (Albrecht, 3/13)

The Charlotte Observer: Cheery Work Environment Shapes Busy Health Care Center
Gateway Ambulatory Surgery Center in Concord stays busy. Local surgeons perform more than 10,000 outpatient procedures a year there, according to the healthcare organization. Still, employees there make time to maintain an upbeat atmosphere at the workplace. They celebrate holidays, hold baking contests and put their own spin on the bring-your-child-to-work theme. (Smith, 3/12)

A selection of opinions from around the country.

Lincoln Journal Star: Facts Support Medcaid Reform
Here’s a simplified explanation of how Medicaid expansion is funded. Imagine an optional program available to 10 members for a shekel a year. All the members will share in the funding regardless of whether they participate. If five members participate, the cost of five shekels is divided among the members at a cost of half a shekel each. In other words, the non-participating members send their half-shekel to the participants. If all members sign up for the optional program, the cost for each goes up to a shekel each, and all receive the benefits of the program. (3/12)

The Detroit Free Press: Mich. Should Not Privatize Mental Health Services
The future of the local public mental health agencies that have successfully served this population for decades is now in jeopardy thanks to Gov. Rick Snyder’s latest annual budget proposal, which would would transfer mental health funding to for-profit health insurance firms. (Hair, 3/12)

Modern Healthcare: Keep CMS' Value-Based Pay Off My Medicare Drugs!
Everyone is in favor of value-based reimbursement in healthcare, right? If you're still wearing those rose-colored glasses, take a closer look at last week's reaction to Medicare's proposal to test new ways of paying for drugs administered in physician offices and hospital outpatient departments. (Merrill Goozner, 3/12)

The Arizona Republic: Tell Andy Biggs That KidsCare Deserves A Vote
Arizona has the highest rate of uninsured children among the families who would benefit most from the restoration of the program. Restoration would allow KidsCare to once again bring health care to children whose families make too much to qualify for the state’s Medicaid program, but too little to buy insurance on their own. These are children of the working poor. (3/12)

The Arizona Republic: VA Is Fighting More Choices For Veterans
More than a year after I led the fight in Congress to pass major bipartisan legislation that enacted the most significant VA reform in a decade, the system is still not working for our veterans. I am frustrated and outraged by the slow nature of change at the VA. I know our veterans are, too. (John McCain, 3/13)

Los Angeles Times: Why A 'Smoking Age' Of 21 Is A Bad Idea
When California lawmakers voted last week to raise the smoking age from 18 to 21, the debate featured optimistic rhetoric that fines and bans would sharply reduce the number of young adults buying or using tobacco. This seemingly common-sense approach, however, doesn't work. There is virtually no systematic research showing that increasing the smoking age prevents a teen from picking up the habit. The Institute of Medicine acknowledged as much in a 2015 report, even as it optimistically projected a 12% decline in adult smokers if the minimum legal age for buying tobacco were 21 nationwide. (Mike Males, 3/11)

The Washington Times: When Health Insurance Fails
Late last year while playing tennis I reached up to serve and I felt a painful pop in my shoulder. The inflammation got worse over the next few months. Now anytime I try to put my arm above my head, pain shoots up my arm. I often wake up at night with an agonizing throb in my shoulder. So I finally and reluctantly went to the orthopedic surgeon and he said that I had a rotator cuff tear and I probably would need surgery. Ugh. He scheduled me for an MRI but the day I was set to go, the hospital called to tell me my insurance company declined to pay for the scans. The insurance company, CIGNA, tersely sent me a note: “You will need to complete six weeks of conservative treatment, such as physical therapy and anti-inflammatory medication. Once that has been completed and you have been re-evaluated, we can try to have the MRI re-authorized.” Gee, thanks. You guys are the best. (Stephen Moore, 3/13)

Reuters: Beating Companies With Taxes Until Revenue Improves Is Nonsense
Now lawmakers at the state level are joining in on the demagoguery, with legislation that would punish employers for bad federal tax policy. In response to Pfizer’s November announcement that it is buying Allergen and moving its headquarters to Ireland, where the 12.5 percent corporate rate is less than one half of the 35 percent imposed by the United States, the New Jersey Assembly passed legislation that prohibits inverted companies from receiving state contracts or development tax credits. (Grover G. Norquist and Patrick Gleason, 3/14)

Modern Healthcare: Executives Must Commit To Lifelong Learning In Relentless Pursuit Of Quality Improvement
The forefront of the healthcare profession is a continually moving target. But what isn't changing are the characteristics that distinguish excellent leaders: They invest in themselves, in others and in their communities. The need for healthcare executives to invest in and expand their professional competencies and leadership capabilities has never been greater. (Edward Lamb, 3/12)

The Chicago Tribune: Brandi Chastain's Brain
In 1999 Brandi Chastain scored the winning shootout goal in the World Cup soccer final against China, then stripped off her jersey and sank to her knees in exultation, arms thrust skyward. Another image of Chastain recently emerged: Now 47, a mother and a coach, the soccer star announced that at death she will donate her brain to the Concussion Legacy Foundation at Boston University, where researchers study chronic traumatic encephalopathy, the degenerative brain disease linked to concussions and head trauma. (3/11)

The Washington Post: What Happened After My Mom Fell
In the Land of the Falling Moms, every obstacle beckons with a kind of gravity. The curled corner of a rug. The slightly raised entryway. The uneven sidewalk. The slick tile. In the Land of the Falling Moms, the difference between upright and upended is measured in inches, but the consequences are calculated in months. (Stephen J. Lyons, 3/11)


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